赵妍
副教授
学历/学位
博士研究生 电子邮件 zongyuan0131 @163.com
职称
副教授
招生专业/类别
学术型、专业型
一、基本情况
赵妍，博士研究生，副教授，zongyuan0131 @163.com。
二、目前研究领域
可解释机器学习在中药药效物质研究的应用；
中药治疗肠易激综合征等肠道疾病的作用机制
三、学习及工作经历
韩国忠南国立大学，药物化学，博士
吉林农业大学，中药学，学士：
烟台大学，药学院，讲师
烟台大学，药学院，副教授
四、主要科研成果
基于可解释机器学习的葛根芩连汤重塑肠道微生态治疗 IBS-D 功效成分群及机制研究，国家自然科学基金青年项目，2026.01-2028.12，主持
荷叶碱调控PPARγ 抑制极低密度脂蛋白分泌改善高脂血症的机制研究，山东省自然科学基金青年项目，2024.01- 2026.12，主持
五、发表论文
Nuciferine activates intestinal TAS2R46 to attenuate metabolic disorders and hyperlipidemia via hepatic VLDL regulation, Phytomedicine, 142, 156800.
Potent β-glucuronidase inhibition by brown algae Ecklonia cava secondary metabolites: Structural characterization, enzyme kinetics, and computational simulations, International Journal of Biological Macromolecules, 327, 147487.
An interpretable screening approach derived through XGBoost regression for the discovery of hypolipidemic contributors in Chinese hawthorn leaf and its counterfeit Malus doumeri leaf, Plant Foods for Human Nutrition, 2024, 79(1): 209-218.
Explainable machine learning-assisted origin identification: Chemical profiling of five lotus (Nelumbo nucifera Gaertn.) parts, Food Chemistry, 2023, 404: 134517.
Valorization of the industrial waste of two uncommon parts from lotus (Nelumbo nucifera Gaertn.): Insight to phytochemicals and hypolipidemic potential, Industrial Crops and Products, 2022, 188, 115596.
Estimating the Q-marker concentrations of Salvia miltiorrhiza via a long short-term memory algorithm using climatic factors and metabolic profiling, Industrial Crops Products, 2020, 156, 112883.
A comprehensive analytical platform for unraveling the effect of the cultivation area on the composition of Salvia miltiorrhiza Bunge, Industrial Crops and Products, 2020, 145, 111952.
Characterization and classification of three common Bambusoideae species in Korea by an HPLC-based analytical platform coupled with multivariate statistical analysis, Industrial Crops and Products, 2019, 130, 389–397.
六、授权专利情况
一种预测丹参中质量标志物含量的方法，2022-03-01，中国， CN202010699837.5
指导研究生情况
已毕业 4 名，在读 3 名。