王琳

副教授

• 学历/学位

  博士

• 职称

  副教授

• 电子邮箱

  rushanwanglin@126.com

• 招生专业/类别

  药学/学硕、专硕

一、基本情况

王琳，博士，副教授，rushanwanglin@126.com。

二、目前研究领域

药物代谢动力学

中药药效物质基础研究

三、学习及工作经历

• 2008.09-2012.06

  中国药科大学药学院，本科

• 2012.09-2017.06

  中国药科大学药学院，博士

• 2017.07-2019.12

  烟台药物研究所，工程师

• 2020.01-至今

  烟台大学，教师

四、主要科研成果

1. Qian F, Ouyang B1, Cai Z, Zhu D, Yu S, Zhao J, Wei N, Wang G,Wang L*, Zhang J*. Compound Shouwu Jiangzhi Granule regulates triacylglyceride synthesis to alleviate hepatic lipid accumulation. Phytomedicine. 2024 Jul;129:155691.

2. Su M, Liu X, Zhao Y, Zhu Y, Wu M, Liu K, Yang G, Liu W*, Wang L*. In Silico and In Vivo Pharmacokinetic Evaluation of 84-B10, a Novel Drug Candidate againstAcute Kidney Injury and Chronic Kidney Disease. Molecules. 2023 Dec 27;29(1):159.

3. Lin C, Kong Y, Wang F, Rong R, Li X, Xiao R, Wu Z, Zhang Q*, Wang L*. Design, synthesis and evaluation of a series of novel long-acting dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes. Bioorg Chem. 2022 Jun;123:105767.

4. Wang L, Li X, Kong Y, Wang F, Zhang Q, Lin C*, Rong R*. Pharmacokinetics, tissue distribution and excretion of compound 6c, a novel DPP-4 inhibitor, following intragastric administration in rats by ultra-performance liquid chromatography-tandem mass spectrometry. Eur J Pharm Sci. 2022 Jun 1;173:106162.

5. Wang L, Lei H, Lu J, Wang W, Liu C, WangY, YangY, Tian J*, Zhang J*. Study on Pharmacokinetics and Metabolic Profiles of Novel Potential PLK-1 Inhibitors by UHPLC-MS/MS Combined with UHPLC-Q-Orbitrap/HRMS. Molecules. 2023 Mar 10;28(6):2550.

指导研究生情况

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