刘荣霞

教授

• 学历/学位

  博士

• 职称

  教授

• 电子邮箱

  liurongxia107@aliyun.com

• 招生专业/类别

  药学

一、基本情况

刘荣霞，博士，教授，烟台大学药学院教师，从事中药复杂体系质量控制及药物代谢分析研究。

二、学习及工作经历

• 2021-至今

  教授，烟台大学

• 2015-2020

  副教授，烟台大学

• 2012-2014

  欧盟“玛丽·居里”学者，维也纳大学生药系

• 2008-2012

  高级研究员，GSK R&D, China

• 2005-2007

  助理研究员，中国科学院上海药物研究所

• 2000-2005

  博士，北京大学医学部与沈阳药科大学联合培养

• 1995-2000

  学士，沈阳药科大学，英语药学专业

三、社会兼职

Journal of Ethnopharmacology，Planta Medica，Phytomedicine，Journal of Pharmaceutical and Biomedical Analysis等国际杂志审稿人；国家自然科学基金委通讯评审专家；山东省分析测试协会会员；烟台药学会理事。

四、目前研究领域

• 中药复杂体系的质量控制研究

• 药物代谢和体内微量物质分析研究

• 抗心血管疾病的药物筛选及作用机制研究

五、代表性科研项目、成果和奖励

项目

• 基于TRPV1通道探讨辛味中药抑制血管平滑肌细胞增殖的作用机制，国家自然科学基金，面上，54万，主持

• 迷迭香酸类成分作为新的血管平滑肌细胞增殖抑制剂的发现和机理研究，国家自然科学基金，青年，17万，主持

• 基于调控“PLK4/中心体扩增”的吴茱萸生物碱治疗血管增殖疾病作用机制研究，山东省自然科学基金，10万，主持

• 巨噬细胞极化、骨髓干细胞影响动脉粥样硬化发生的Notch信号介导机制，山东省自然科学基金，13万，参与

• 欧盟第七研发框架计划中的“玛丽·居里行动计划”人才国际引进项目（Marie Curie International Incoming Fellowships），欧盟，主持

奖励

中华人民共和国教育部，高等学校科学技术奖，自然科学一等奖（2007005）：中药复杂体系成分分析及体内过程研究（参与）

已发表论文60余篇，近三年部分论文

1. Na Li, Qiuyue Huang, Yu Liu, Dongju Ren, Yanchen Liu, Xinyu Liu, Peng Zhang**, Rongxia Liu*. Bovine serum albumin-coated metal-phenolic nanoplatform for atherosclerosis therapy via targeted delivery and inhibition of vascular smooth muscle cells proliferation. Free Radical Biology and Medicine, 2026, 251: 372. (IF 8.2, 一区, Top期刊)

2. Chenglin Chi, Xiaoli Yang, Can Li, Zongchao Li, Shufang Yang, Yuan Du*, Weizhen Huang*, Rongxia Liu*. The Tetradium ruticarpum-Zingiber officinale Roscoe herb pair inhibits atherogenic events: A study of the synergistic effects and active ingredient combination of a two-herb formula. Fitoterapia 2026, 188: 107030.

3. Patricia Haiss, Rongxia Liu, Feng Xian, David Gomez Varela, Manuela Schmidt, Verena M. Dirsch, Tina Blazevic. Evodiamine induces centrosome amplification with subsequent G2/M cell cycle arrest in primary vascular smooth muscle cells [J]. Biochemical Pharmacology, 2025, 242: 117320. (二区)

4. Xiaoxue Jiang, Ruoxuan Xu, Yu Liu, Dongju Ren, Shufang Yang, Yan Zhao**, Rongxia Liu*. Unveiling the dynamic migration and intrinsic relations between predominant bioactivities and metabolic profiles in persimmon leaves [J]. Food Bioscience, 2025, 68: 106487. (IF 6.2, 一区, Top期刊)

5. Yanyan Zhang, Na Li, Yu Liu, Dongju Ren, Rongxia Liu*. Chemometrics bridges the metabolic profiling and biological activities of Functional Qu, Ordinary Qu, and Wuyi Qu from three Hongqu cultivars. Food Bioscience, 2025, 68: 106683. (IF 6.2, 一区, Top期刊)

6. Yanyan Zhang, Dongju Ren, Yu Liu, Na Li, Xiaoli Yang, Shufang Yang, Rongxia Liu*. Mechanism of Red Yeast Rice in the Improvement of Atherosclerosis in Apolipoprotein E-deficient Mice Explored Through Metabolomics Combined with Serum Pharmacochemistry and Network Pharmacology. Plant Foods for Human Nutrition, 2025, 80: 140. (二区)

7. Shufang Yang, Xiaoxue Jiang, Ruoxuan Xu, Yanyan Zhang, Rongxia Liu*. Development of an underutilized part of Syzygium aromaticum based on phytochemical and bioactivity assessment. Food Chemistry, 2025, 481: 144072. (IF 9.8, 一区, Top期刊)

8. Shufang Yang, Zongchao Li, Wenjing Li, Can Li, Xiaoli Yang, Yan Zhao*, Rongxia Liu*. Unraveling the variations and relationships between phytochemical constituents and anti-inflammatory potentials of three Zanthoxylum species through metabolomics and explainable machine learning. Industrial Crops & Products, 2024, 212: 118281. (IF 5.9, 一区, Top期刊)

9. Jingxian Huang, Zhen Li, Wei Zhang, Zhuoyuan Lv, Shuying Dong, Yan Feng, Rongxia Liu*, Yan Zhao*. Explainable machine learning-assisted origin identification: Chemical profiling of five lotus (Nelumbo nucifera Gaertn.) parts. Food Chemistry, 2023, 404: 134517. (IF 8.8, 一区, Top期刊)

10. Xiaoli Yang, Chenglin Chi, Wenjing Li, Yanyan Zhang, Shufang Yang, Ruoxuan Xu, Rongxia Liu*. Metabolomics and lipidomics combined with serum pharmacochemistry uncover the potential mechanism of Huang-Lian-Jie-Du decoction alleviates atherosclerosis in ApoE-/- mice. Journal of Ethnopharmacology, 2024: 117748. (二区)

11. Kang Sun, Zongchao Li, Wenjing Li, Chenglin Chi, Minjun Wang, Ruoxuan Xu, Yan Gao, Bing Li, Yiying Sun, Rongxia Liu*. Investigating the anti-atherosclerotic effects and potential mechanism of Dalbergia odorifera in ApoE-deficient mice using network pharmacology combined with metabolomics. Journal of Pharmaceutical and Biomedical Analysis. 2024, 242: 116017.

六、指导研究生情况

已毕业17名，在读3名。